Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 18/20 | 0.66 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23315193 | 0.89 | AGTR2 (0.81) | AGTR2AGTR1 | |
| SCHEMBL23315246 | 0.89 | AGTR2 (0.81) | AGTR2AGTR1 | |
| SCHEMBL23315237 | 0.89 | AGTR2 (0.81) | AGTR2AGTR1 | |
| SCHEMBL10073578 | 0.85 | AGTR2 (0.81) | AGTR2AGTR1 | |
| SCHEMBL23315568 | 0.85 | AGTR2 (0.77) | AGTR2AGTR1 | |
| SCHEMBL23315510 | 0.84 | AGTR2 (0.75) | AGTR2AGTR1 | |
| SCHEMBL23315475 | 0.84 | AGTR2 (0.75) | AGTR2AGTR1 | |
| SCHEMBL23315487 | 0.81 | AGTR2 (0.63) | AGTR2AGTR1 | |
| SCHEMBL23315319 | 0.81 | AGTR2 (0.63) | AGTR2AGTR1 | |
| SCHEMBL8964042 | 0.80 | AGTR2 (1.00) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3620454-B1 | CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-05-05 | — | — | EP | disclosed |