Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 14/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21881527 | 0.90 | AGTR2 (0.58) | AGTR2AGTR1HDAC8PTPN1 | |
| SCHEMBL21881522 | 0.90 | AGTR2 (0.58) | AGTR2AGTR1HDAC8PTPN1 | |
| SCHEMBL21881810 | 0.90 | AGTR2 (0.52) | AGTR2AGTR1HDAC8PTPN1 | |
| SCHEMBL21881523 | 0.90 | AGTR2 (0.52) | AGTR2AGTR1HDAC8PTPN1 | |
| SCHEMBL21881852 | 0.89 | AGTR2 (0.52) | AGTR2AGTR1HDAC8PTPN1 | |
| SCHEMBL21881530 | 0.89 | AGTR2 (0.52) | AGTR2AGTR1HDAC8PTPN1 | |
| SCHEMBL23315479 | 0.89 | AGTR2 (0.51) | AGTR2AGTR1HDAC8PTPN1 | |
| SCHEMBL21881602 | 0.89 | AGTR2 (0.51) | AGTR2AGTR1HDAC8PTPN1 | |
| SCHEMBL21881841 | 0.87 | AGTR2 (0.48) | AGTR2AGTR1HDAC8PTPN1 | |
| SCHEMBL21881596 | 0.84 | PTPN1 (0.46) | AGTR2AGTR1HDAC8PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3620454-B1 | CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-05-05 | — | — | EP | disclosed |