Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335422 | 0.89 | HTR4 (0.53) | HTR4 | |
| SCHEMBL2333567 | 0.84 | HTR4 (0.45) | HTR4OPRM1OPRL1OPRD1MEN1 | |
| SCHEMBL2333316 | 0.83 | HTR4 (0.44) | HTR4OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL2337297 | 0.83 | HTR4 (0.48) | HTR4OPRM1OPRL1OPRD1MEN1 | |
| SCHEMBL3297464 | 0.81 | HTR4 (0.46) | HTR4OPRM1OPRL1OPRD1KCNH2 | |
| Hydrochloric Acid SCHEMBL3297560 | 0.81 | HTR4 (0.45) | HTR4OPRM1OPRL1OPRD1KCNH2 | |
| SCHEMBL2334884 | 0.79 | HTR4 (0.46) | HTR4OPRM1OPRL1 | |
| SCHEMBL2338629 | 0.78 | HTR4 (0.44) | HTR4OPRM1 | |
| SCHEMBL15103640 | 0.75 | HTR4 (0.49) | HTR4OPRM1OPRL1OPRD1KCNH2 | |
| SCHEMBL18298116 | 0.74 | HTR4 (0.42) | HTR4OPRM1OPRL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358702-A2 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK Holdings Co., Ltd. (KR) | 2011-08-24 | — | — | EP | claimed |
| WO-2010044585-A2 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK HOLDINGS CO., LTD. (KR) | 2010-04-22 | — | — | WO | claimed |
| EP-2358702-A2 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK Holdings Co., Ltd. (KR) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010044585-A2 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK HOLDINGS CO., LTD. (KR) | 2010-04-22 | — | — | WO | disclosed |