Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 12/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23315338 | 0.89 | AGTR2 (0.57) | AGTR2AGTR1HCRTR2KDM4EALDH1A1 | |
| SCHEMBL23315290 | 0.88 | AGTR2 (0.57) | AGTR2AGTR1HCRTR2KDM4EALDH1A1 | |
| SCHEMBL23315639 | 0.85 | AGTR2 (0.52) | AGTR2AGTR1HCRTR2SCN9A | |
| SCHEMBL21881313 | 0.85 | AGTR2 (0.61) | AGTR2AGTR1 | |
| SCHEMBL21881307 | 0.85 | AGTR2 (0.61) | AGTR2AGTR1 | |
| SCHEMBL21881361 | 0.85 | AGTR2 (0.61) | AGTR2AGTR1 | |
| SCHEMBL23315451 | 0.85 | AGTR2 (0.61) | AGTR2AGTR1 | |
| SCHEMBL21881311 | 0.85 | AGTR2 (0.61) | AGTR2AGTR1 | |
| SCHEMBL21881308 | 0.85 | AGTR2 (0.61) | AGTR2AGTR1 | |
| SCHEMBL23315354 | 0.84 | AGTR2 (0.55) | AGTR2AGTR1HCRTR2HCRTR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3620454-B1 | CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-05-05 | — | — | EP | disclosed |