SCHEMBL2331578

SCHEMBL2331578

CC(C)COBO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1272132 0.79
SCHEMBL432519 0.73 ALDH1A1 (0.36)
SCHEMBL13530904 0.71
SCHEMBL30593075 0.69
SCHEMBL8680394 0.68
SCHEMBL5552740 0.67
SCHEMBL1271479 0.65
SCHEMBL25435787 0.62 TSHR (0.54)
SCHEMBL37351 0.62 TSHR (0.54)
SCHEMBL374667 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240083922-A1 Proteasome Inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-03-14 US disclosed
US-20230265110-A1 Proteasome Inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-08-24 US disclosed
US-20220251117-A1 PROTEASOME INHIBITORS MILLENNIUM PHARMACEUTICALS, INC. 2022-08-11 US disclosed
US-20220017542-A1 PROTEASOME INHIBITORS MILLENNIUM PHARMACEUTICALS, INC. 2022-01-20 US disclosed
US-20210206784-A1 PROTEASOME INHIBITORS MILLENNIUM PHARMACEUTICALS, INC. 2021-07-08 US disclosed
US-20200407376-A1 PROTEASOME INHIBITORS MILLENNIUM PHARMACEUTICALS, INC. 2020-12-31 US disclosed
US-20200190118-A1 PROTEASOME INHIBITORS MILLENNIUM PHARMACEUTICALS, INC. 2020-06-18 US disclosed
US-20190144470-A1 PROTEASOME INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-05-16 US disclosed
US-20180305380-A1 PROTEASOME INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-10-25 US disclosed
US-20180145267-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-24 US disclosed
US-20110301124-A1 PROTEASOME INHIBITORS MILLENNIUM PHARMACEUTICALS, INC. (US) 2011-12-08 US disclosed
US-8003819-B2 Proteasome inhibitors MILLENNIUM PHARMACEUTICALS, INC. (US) 2011-08-23 US disclosed
US-20100204180-A1 PROTEASOME INHIBITORS MILLENNIUM PHARMACEUTICALS, INC. (US) 2010-08-12 US disclosed
EP-2178888-A1 PROTEASOME INHIBITORS Millennium Pharmaceuticals, Inc. (US) 2010-04-28 EP disclosed
US-7687662-B2 e.g. 1-({[(2,3-difluorobenzoyl)amino]acetyl}amino)-3-methylbutyl]boronic acid; anticarcinogenic, antiproliferative agent MILLENNIUM PHARMACEUTICALS, INC. (US) 2010-03-30 US disclosed
US-20090069171-A1 Catalysts for olefin polymerization, process for production of the catalysts, and method for preservation thereof JAPAN POLYPROPYLENE CORPORATION (JP) 2009-03-12 US disclosed
WO-2009020448-A1 PROTEASOME INHIBITORS MILLENNIUM PHARMACEUTICALS, INC. (US) 2009-02-12 WO disclosed
US-20090042836-A1 e.g. 1-({[(2,3-difluorobenzoyl)amino]acetyl}amino)-3-methylbutyl]boronic acid; anticarcinogenic, antiproliferative agent MILLENNIUM PHARMACEUTICALS, INC. (US) 2009-02-12 US disclosed
US-7442830-B1 Proteasome inhibitors MILLENIUM PHARMACEUTICALS, INC. (US) 2008-10-28 US disclosed
EP-1881012-A1 CATALYSTS FOR OLEFIN POLYMERIZATION, PROCESS FOR PRODUCTION OF THE CATALYSTS, AND METHOD FOR PRESERVATION THEREOF Japan Polypropylene Corporation (JP) 2008-01-23 EP disclosed