Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23621921 | 1.00 | IDH1 (0.60) | IDH1 | |
| SCHEMBL23316598 | 1.00 | IDH1 (0.60) | IDH1 | |
| SCHEMBL23316443 | 0.94 | IDH1 (0.61) | IDH1 | |
| SCHEMBL23316566 | 0.94 | IDH1 (0.61) | IDH1 | |
| SCHEMBL23316514 | 0.94 | IDH1 (0.61) | IDH1 | |
| SCHEMBL23316596 | 0.94 | IDH1 (0.59) | IDH1 | |
| SCHEMBL23621922 | 0.94 | IDH1 (0.59) | IDH1 | |
| SCHEMBL23316597 | 0.94 | IDH1 (0.59) | IDH1 | |
| SCHEMBL26655819 | 0.93 | IDH1 (0.53) | IDH1 | |
| SCHEMBL26661885 | 0.93 | IDH1 (0.53) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3816158-B1 | BENZIMIDAZOLE DERIVATIVES AND USE THEREOF AS IDH1 INHIBITORS | KPC PHARMACEUTICALS INC (CN) | 2023-10-25 | — | — | EP | disclosed |
| US-11407717-B2 | Benzimidazole derivatives and use thereof as IDH1 inhibitors | KPC PHARMACEUTICALS, INC. (CN) | 2022-08-09 | — | — | US | disclosed |
| US-20210206728-A1 | BENZIMIDAZOLE DERIVATIVES AND USE THEREOF AS IDH1 INHIBITORS | KPC PHARMACEUTICALS, INC. (CN) | 2021-07-08 | — | — | US | disclosed |
| EP-3816158-A1 | BENZIMIDAZOLE DERIVATIVES AND USE THEREOF AS IDH1 INHIBITORS | KPC Pharmaceuticals, Inc. (CN) | 2021-05-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11407717-B2 | Benzimidazole derivatives and use thereof as IDH1 inhibitors | IDH1, IDH3A, IDH2 | IDH1 1/4885 |
| US-20210206728-A1 | BENZIMIDAZOLE DERIVATIVES AND USE THEREOF AS IDH1 INHIBITORS | IDH1, IDH3A, IDH2 | IDH1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.