Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26661885 | 1.00 | IDH1 (0.53) | IDH1 | |
| SCHEMBL23316524 | 0.94 | IDH1 (0.51) | IDH1 | |
| SCHEMBL23316598 | 0.93 | IDH1 (0.60) | IDH1 | |
| SCHEMBL23316599 | 0.93 | IDH1 (0.60) | IDH1 | |
| SCHEMBL23621921 | 0.93 | IDH1 (0.60) | IDH1 | |
| SCHEMBL23316706 | 0.93 | IDH1 (0.61) | IDH1 | |
| SCHEMBL23316707 | 0.93 | IDH1 (0.61) | IDH1 | |
| SCHEMBL23316566 | 0.87 | IDH1 (0.61) | IDH1 | |
| SCHEMBL23316514 | 0.87 | IDH1 (0.61) | IDH1 | |
| SCHEMBL23316443 | 0.87 | IDH1 (0.61) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3816158-B1 | BENZIMIDAZOLE DERIVATIVES AND USE THEREOF AS IDH1 INHIBITORS | KPC PHARMACEUTICALS INC (CN) | 2023-10-25 | — | — | EP | disclosed |