Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 19/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.38 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23316461 | 0.87 | PIK3CD (0.38) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL23316641 | 0.87 | PIK3CD (0.46) | PIK3CDPIK3CGPIK3CBPIK3R1 | |
| SCHEMBL17724012 | 0.85 | PIK3CD (0.43) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL23316419 | 0.77 | PIK3CD (0.56) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL23316453 | 0.76 | PIK3CD (0.52) | PIK3CDPIK3CGPIK3CBPIK3R1 | |
| SCHEMBL17724011 | 0.74 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL17713865 | 0.74 | PIK3CD (0.60) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL17397284 | 0.73 | PIK3CD (0.62) | PIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL17401174 | 0.73 | PIK3CD (0.62) | PIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL17401127 | 0.73 | PIK3CD (0.62) | PIK3CDPIK3CGPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3224248-B1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2021-05-05 | — | — | EP | disclosed |