Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29914267 | 0.89 | HRH3 (0.40) | HRH3AVPR1A | |
| SCHEMBL23304903 | 0.89 | HRH3 (0.40) | HRH3AVPR1A | |
| SCHEMBL23317207 | 0.88 | AVPR1A (0.31) | AVPR1A | |
| SCHEMBL23317324 | 0.88 | AVPR1A (0.34) | KCNH2AVPR1A | |
| SCHEMBL23317423 | 0.86 | AVPR1A (0.34) | OPRM1KCNH2AVPR1A | |
| SCHEMBL23317310 | 0.82 | AVPR1A (0.33) | SIGMAR1OPRM1OPRK1KCNH2AVPR1A | |
| SCHEMBL23305009 | 0.78 | OGA (0.36) | — | |
| SCHEMBL23306083 | 0.78 | OGA (0.36) | AVPR1A | |
| SCHEMBL23304714 | 0.78 | OGA (0.36) | — | |
| SCHEMBL29914317 | 0.78 | OGA (0.36) | AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021086966-A1 | SPIROCYCLIC O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2021-05-06 | — | — | WO | disclosed |