Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 4/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CCNH | P51946 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23305003 | 0.90 | OGA (0.37) | AVPR1A | |
| SCHEMBL23317427 | 0.86 | SIGMAR1 (0.38) | AVPR1AOPRM1KCNH2 | |
| SCHEMBL23317207 | 0.82 | AVPR1A (0.31) | AVPR1A | |
| SCHEMBL23317324 | 0.82 | AVPR1A (0.34) | AVPR1AKCNH2 | |
| SCHEMBL23317310 | 0.76 | AVPR1A (0.33) | AVPR1AOPRM1KCNH2 | |
| SCHEMBL23317511 | 0.76 | CHRNB2 (0.34) | OPRM1KCNH2 | |
| SCHEMBL29914267 | 0.76 | HRH3 (0.40) | AVPR1AOPRL1 | |
| SCHEMBL23304903 | 0.76 | HRH3 (0.40) | AVPR1AOPRL1 | |
| SCHEMBL23305313 | 0.76 | OGA (0.39) | — | |
| SCHEMBL29914299 | 0.76 | OGA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021086966-A1 | SPIROCYCLIC O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2021-05-06 | — | — | WO | disclosed |