SCHEMBL23317826

SCHEMBL23317826

O=C(O)c1cnn2ccc(N3OCC[C@@H]3c3cc(F)cnc3O)nc12

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NTRK1 P04629 19/20 0.48
JAK2 O60674 15/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22849675 1.00 NTRK1 (0.48) NTRK1JAK2
SCHEMBL23317821 0.88 NTRK1 (0.47) NTRK1JAK2
SCHEMBL22849828 0.88 NTRK1 (0.47) NTRK1JAK2
SCHEMBL22849673 0.85 NTRK1 (0.62) NTRK1JAK2
SCHEMBL23317823 0.85 NTRK1 (0.62) NTRK1JAK2
SCHEMBL21911084 0.84 NTRK1 (0.56) NTRK1JAK2
SCHEMBL22880650 0.82 NTRK1 (0.49) NTRK1JAK2
SCHEMBL24833907 0.82 NTRK1 (0.34) NTRK1JAK2
SCHEMBL24833916 0.82 NTRK1 (0.34) NTRK1JAK2
SCHEMBL23149413 0.82 NTRK1 (0.70) NTRK1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021083345-A1 PREPARATION METHOD FOR PYRAZOLOPYRIMIDINE COMPOUND AND INTERMEDIATE THEREOF 先声药业有限公司 2021-05-06 WO disclosed