Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 19/20 | 0.34 |
| ▸ | JAK2 | O60674 | 7/20 | 0.34 |
| ▸ | ROS1 | P08922 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24833916 | 1.00 | NTRK1 (0.34) | NTRK1JAK2ROS1 | |
| SCHEMBL24833914 | 0.88 | NTRK1 (0.34) | NTRK1JAK2 | |
| SCHEMBL24833915 | 0.87 | NTRK1 (0.40) | NTRK1JAK2 | |
| SCHEMBL24833960 | 0.86 | NTRK1 (0.45) | NTRK1JAK2 | |
| SCHEMBL24833909 | 0.86 | NTRK1 (0.42) | NTRK1JAK2 | |
| SCHEMBL23317826 | 0.82 | NTRK1 (0.48) | NTRK1JAK2 | |
| SCHEMBL22849675 | 0.82 | NTRK1 (0.48) | NTRK1JAK2 | |
| SCHEMBL24834661 | 0.80 | NTRK1 (0.52) | NTRK1JAK2 | |
| SCHEMBL24834665 | 0.80 | NTRK1 (0.52) | NTRK1JAK2 | |
| SCHEMBL23317821 | 0.73 | NTRK1 (0.47) | NTRK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002410-A1 | COMPOUND AS HIGHLY SELECTIVE ROS1 INHIBITOR AND USE THEREOF | GUANGZHOU JOYO PHARMATECH CO., LTD. (CN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002410-A1 | COMPOUND AS HIGHLY SELECTIVE ROS1 INHIBITOR AND USE THEREOF | ROS1, NOX1, NOX4 | NTRK1 1543/4885JAK2 17/4885ROS1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.