Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29563815 | 0.90 | TDP1 (0.52) | TRIM24TRIM33TDP1LMNAKMT2A | |
| SCHEMBL40458 | 0.90 | TDP1 (0.52) | TRIM24TRIM33TDP1LMNAKMT2A | |
| Water SCHEMBL8176347 | 0.88 | TDP1 (0.50) | TRIM24TRIM33TDP1LMNAKMT2A | |
| SCHEMBL1302666 | 0.88 | TDP1 (0.50) | TRIM24TRIM33TDP1LMNAKMT2A | |
| SCHEMBL2986619 | 0.88 | TDP1 (0.50) | TRIM24TRIM33TDP1LMNAKMT2A | |
| SCHEMBL30293806 | 0.88 | TDP1 (0.50) | TRIM24TRIM33TDP1LMNAKMT2A | |
| SCHEMBL549939 | 0.88 | TDP1 (0.50) | TRIM24TRIM33TDP1LMNAKMT2A | |
| Water SCHEMBL1403479 | 0.86 | TDP1 (0.48) | TRIM24TRIM33TDP1LMNAKMT2A | |
| Benzaldehyde SCHEMBL4950072 | 0.85 | ALDH1A1 (0.52) | TRIM24TRIM33TDP1LMNAKMT2A | |
| Sulfurous Acid SCHEMBL8747984 | 0.83 | TDP1 (0.44) | TRIM24TRIM33TDP1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130046103-A1 | PREPARATION OF BENZOFURANS AND USE THEREOF AS SYNTHETIC INTERMEDIATES | MAPI PHARMA LIMITED (IL) | 2013-02-21 | — | — | US | disclosed |
| EP-2533636-A1 | PREPARATION OF BENZOFURANS AND USE THEREOF AS SYNTHETIC INTERMEDIATES | Mapi Pharma Limited (IL) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011099010-A1 | PREPARATION OF BENZOFURANS AND USE THEREOF AS SYNTHETIC INTERMEDIATES | MAPI PHARMA HOLDINGS (CYPRUS) LIMITED (CY) | 2011-08-18 | — | — | WO | disclosed |
| US-20080240638-A1 | Rolling bearing | JTEKT CORPORATION (JP) | 2008-10-02 | — | — | US | disclosed |
| US-5446126-A | Dissolving resist in solvent, contacting with cation exchange resin which has been prewashed with quaternary ammonium salt solution, separating resin | OCG MICROELECTRONIC MATERIALS, INC. (US) | 1995-08-29 | — | — | US | disclosed |
| US-5446125-A | Dissolving novolak resist in a solvent, contacting with cation exchange and chelate resins, separating chelate and ion exchange resins from novolak | OCG MICROELECTRONIC MATERIALS, INC. (US) | 1995-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130046103-A1 | PREPARATION OF BENZOFURANS AND USE THEREOF AS SYNTHETIC INTERMEDIATES | CYP2F1, CYP4F3, CYP2D6 | TRIM24 4112/4885TRIM33 4171/4885TDP1 4036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.