Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 11/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23318453 | 0.79 | PTGER4 (0.32) | PTGER4 | |
| SCHEMBL23318279 | 0.74 | RORC (0.44) | RORCNPY5RPTGDR2CNR2 | |
| SCHEMBL23318574 | 0.74 | BRD4 (0.51) | — | |
| SCHEMBL31662502 | 0.69 | KDM4E (0.61) | PTGER4LMNAPTGDR2ALDH1A1HPGD | |
| SCHEMBL23306643 | 0.69 | KDM4E (0.61) | PTGER4LMNAPTGDR2ALDH1A1HPGD | |
| SCHEMBL24115689 | 0.69 | PRSS1 (0.37) | LMNAALDH1A1HPGD | |
| SCHEMBL811819 | 0.66 | POLB (0.55) | LMNAALDH1A1HPGD | |
| SCHEMBL32689427 | 0.66 | POLB (0.55) | LMNAALDH1A1HPGD | |
| SCHEMBL23318385 | 0.65 | CNR2 (0.50) | CNR2 | |
| SCHEMBL11846379 | 0.62 | KRAS (0.43) | RORCPTGER4NPY5RLMNAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087096-A1 | P53 MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-05-06 | — | — | WO | disclosed |