Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.40 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30787846 | 0.90 | AAK1 (0.38) | MCHR1NPY5R | |
| SCHEMBL22547916 | 0.90 | AAK1 (0.38) | MCHR1NPY5R | |
| SCHEMBL4100163 | 0.82 | DRD3 (0.45) | MCHR1DRD2DRD3DRD4 | |
| SCHEMBL4110551 | 0.82 | DRD3 (0.45) | MCHR1DRD2DRD3DRD4 | |
| SCHEMBL4100155 | 0.82 | DRD3 (0.45) | MCHR1DRD2DRD3DRD4 | |
| SCHEMBL4117256 | 0.81 | MCHR1 (0.39) | MCHR1DRD2DRD3FAAH | |
| SCHEMBL4105102 | 0.81 | MCHR1 (0.39) | MCHR1DRD2DRD3FAAH | |
| SCHEMBL4105094 | 0.81 | MCHR1 (0.39) | MCHR1DRD2DRD3FAAH | |
| SCHEMBL6483133 | 0.80 | ACHE (0.45) | HTR2CACHE | |
| SCHEMBL31730506 | 0.80 | SRD5A1 (0.38) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087181-A1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS TOLL RECEPTOR INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-05-06 | — | — | WO | disclosed |