Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 16/20 | 0.65 |
| ▸ | BAZ2A | Q9UIF9 | 15/20 | 0.65 |
| ▸ | BRD9 | Q9H8M2 | 7/20 | 0.51 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.51 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.51 |
| ▸ | TRIM33 | Q9UPN9 | 3/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24510745 | 0.78 | BAZ2B (1.00) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 | |
| SCHEMBL24510741 | 0.72 | BAZ2B (0.57) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 | |
| SCHEMBL24510740 | 0.71 | FNTA (0.60) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 | |
| SCHEMBL24510742 | 0.70 | BAZ2B (0.55) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 | |
| SCHEMBL30427435 | 0.68 | BRD9 (1.00) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 | |
| SCHEMBL26302130 | 0.67 | BAZ2B (0.69) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 | |
| SCHEMBL23318444 | 0.67 | BAZ2B (0.79) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 | |
| SCHEMBL18556097 | 0.65 | FNTA (0.54) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 | |
| SCHEMBL26302067 | 0.65 | BAZ2B (0.53) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 | |
| SCHEMBL29883537 | 0.65 | CREBBP (0.61) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087096-A1 | P53 MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-05-06 | — | — | WO | disclosed |