Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 8/20 | 0.57 |
| ▸ | BAZ2A | Q9UIF9 | 7/20 | 0.57 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.52 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.52 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 2/20 | 0.42 |
| ▸ | FNTB | P49356 | 2/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24510740 | 0.81 | FNTA (0.60) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 | |
| SCHEMBL25400578 | 0.80 | BAZ2B (0.45) | BAZ2BBAZ2ABRD9TP53ALDH1A1 | |
| SCHEMBL24510742 | 0.79 | BAZ2B (0.55) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 | |
| SCHEMBL25402588 | 0.77 | LMNA (0.46) | TP53FNTAFNTBALDH1A1HPGD | |
| SCHEMBL18556097 | 0.75 | FNTA (0.54) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 | |
| SCHEMBL25399546 | 0.75 | BAZ2B (0.38) | BAZ2BBAZ2ABRD9ALDH1A1HPGD | |
| SCHEMBL25401668 | 0.74 | BAZ2B (0.62) | BAZ2BBAZ2ABRD9TP53FNTA | |
| SCHEMBL24510745 | 0.72 | BAZ2B (1.00) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 | |
| SCHEMBL23318447 | 0.72 | BAZ2B (0.65) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 | |
| SCHEMBL18555942 | 0.70 | BAZ2B (0.47) | BAZ2BBAZ2ABRD9SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4259133-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2023-10-18 | — | — | EP | disclosed |
| WO-2022126000-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2022-06-16 | — | — | WO | disclosed |
| WO-2022126000-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2022-06-16 | — | — | WO | disclosed |