Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753750 | 0.88 | ROCK2 (0.43) | ROCK2KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL19201796 | 0.83 | ROCK2 (0.43) | ROCK2KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL26740152 | 0.82 | ELANE (0.37) | KMT2AMEN1SMN1; SMN2L3MBTL1ELANE | |
| SCHEMBL26549546 | 0.82 | ROCK2 (0.40) | ROCK2KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL19901428 | 0.81 | MEN1 (0.54) | ROCK2KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL1753582 | 0.81 | MEN1 (0.54) | ROCK2KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL27305897 | 0.80 | ELANE (0.52) | KMT2AMEN1SMN1; SMN2L3MBTL1ELANE | |
| SCHEMBL18792766 | 0.80 | ELANE (0.46) | ROCK2KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL12157064 | 0.78 | KMT2A (0.43) | ROCK2KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL23420957 | 0.78 | KMT2A (0.43) | ROCK2KMT2AMEN1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128740-A1 | HDAC INHIBITORS-BASED ANTIBODY DRUG CONJUGATES (ADCs) AND USE IN THERAPY | ALFASIGMA S.P.A. (IT) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128740-A1 | HDAC INHIBITORS-BASED ANTIBODY DRUG CONJUGATES (ADCs) AND USE IN THERAPY | ERBB3, HDAC6, ERBB2 | ROCK2 2324/4885KMT2A 29/4885MEN1 3961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.