SCHEMBL23318554

SCHEMBL23318554

CC(C)Oc1ccccc1S(=O)(=O)Nc1ccc2c(c1)CN(C)C(=O)N2

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 20/20 0.79
CREBBP Q92793 1/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29430449 0.89 BRD4 (1.00) BRD4CREBBP
SCHEMBL14721611 0.89 BRD4 (1.00) BRD4CREBBP
SCHEMBL14722139 0.83 BRD4 (1.00) BRD4CREBBP
SCHEMBL14722430 0.82 BRD4 (1.00) BRD4CREBBP
SCHEMBL14723518 0.82 BRD4 (0.78) BRD4CREBBP
SCHEMBL16771914 0.80 BRD4 (0.74) BRD4CREBBP
SCHEMBL30325316 0.80 BRD4 (0.69) BRD4CREBBP
SCHEMBL17753359 0.78 BRD4 (0.81) BRD4CREBBP
SCHEMBL14721830 0.78 BRD4 (0.77) BRD4CREBBP
SCHEMBL16760629 0.78 BRD4 (0.77) BRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021087096-A1 P53 MODULATORS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-05-06 WO disclosed