Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | DHODH | Q02127 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696056 | 0.82 | RAB9A (0.52) | RAB9ADHODHSMN1; SMN2MEN1KMT2A | |
| SCHEMBL21847164 | 0.76 | RAB9A (0.46) | RAB9ADHODHSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2162312 | 0.76 | SMN1; SMN2 (0.59) | RAB9ADHODHSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6209130 | 0.74 | NR4A1 (0.50) | RAB9ADHODHSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4707512 | 0.73 | NR4A1 (0.53) | RAB9ADHODHSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30893836 | 0.73 | NAPRT (0.56) | RAB9ADHODHSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30489177 | 0.73 | NR4A1 (0.53) | RAB9ADHODHSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8319209 | 0.73 | NAPRT (0.56) | RAB9ADHODHSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4511127 | 0.73 | NR4A1 (0.53) | RAB9ADHODHSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2161994 | 0.72 | NR4A1 (0.51) | RAB9ADHODHSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11186588-B2 | 6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,2,4]triazepine derivative | AYUMI PHARMACEUTICAL CORPORATION (JP) | 2021-11-30 | — | — | US | disclosed |
| US-20210130367-A1 | 6H-THIENO[2,3-e][1,2,4]TRIAZOLO[3,4-c][1,2,4]TRIAZEPINE DERIVATIVE | AYUMI PHARMACEUTICAL CORPORATION (JP) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130367-A1 | 6H-THIENO[2,3-e][1,2,4]TRIAZOLO[3,4-c][1,2,4]TRIAZEPINE DERIVATIVE | BRD4, BRD3, BRD2 | RAB9A 3214/4885DHODH 3933/4885SMN1; SMN2 3608/4885 |
| US-11186588-B2 | 6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,2,4]triazepine derivative | BRD4, BRD3, BRD2 | RAB9A 3214/4885DHODH 3933/4885SMN1; SMN2 3608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.