SCHEMBL23320186

SCHEMBL23320186

O=CCOCCOCCN(C(=O)O)c1ccc2c(c1)c1cccnc1n2C1CCC(=O)NC1=O

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 20/20 0.54
CRBN Q96SW2 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24764478 0.91 DDB1 (0.60) DDB1CRBN
SCHEMBL24764819 0.83 DDB1 (0.71) DDB1CRBN
SCHEMBL30043350 0.83 DDB1 (0.71) DDB1CRBN
SCHEMBL23320184 0.83 DDB1 (0.62) DDB1CRBN
SCHEMBL31711482 0.82 DDB1 (0.60) DDB1CRBN
SCHEMBL23320188 0.82 DDB1 (0.60) DDB1CRBN
SCHEMBL23320187 0.81 DDB1 (0.64) DDB1CRBN
SCHEMBL27085643 0.79 DDB1 (0.69) DDB1CRBN
SCHEMBL24765197 0.78 DDB1 (0.82) DDB1CRBN
SCHEMBL30042705 0.78 DDB1 (0.82) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3817822-A1 PROTEIN DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2021-05-12 EP disclosed