Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15597459 | 0.81 | CASP3 (0.61) | NAMPTCASP3SENP8SENP7SENP6 | |
| SCHEMBL23320381 | 0.79 | NAMPT (1.00) | NAMPTCASP3SENP8SENP7SENP6 | |
| SCHEMBL26932280 | 0.78 | CASP3 (0.73) | NAMPTCASP3SENP8SENP7SENP6 | |
| SCHEMBL29802221 | 0.78 | CASP3 (0.73) | NAMPTCASP3SENP8SENP7SENP6 | |
| SCHEMBL23320402 | 0.78 | NAMPT (0.81) | NAMPTCASP3SENP8SENP7SENP6 | |
| SCHEMBL16817733 | 0.78 | NAMPT (0.65) | NAMPTCASP3SENP8SENP7SENP6 | |
| SCHEMBL2248517 | 0.77 | SMN1; SMN2 (0.72) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL29802104 | 0.76 | CASP3 (0.70) | NAMPTCASP3SENP8SENP7SENP6 | |
| SCHEMBL26932215 | 0.76 | CASP3 (0.70) | NAMPTCASP3SENP8SENP7SENP6 | |
| SCHEMBL29802090 | 0.76 | CASP3 (0.70) | NAMPTCASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | claimed |
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |