Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.59 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.56 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HTR1E | P28566 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30949589 | 0.82 | GAA (0.51) | KCNMA1NR3C1CXCR1CXCR2KMT2A | |
| SCHEMBL30949580 | 0.82 | GAA (0.51) | KCNMA1NR3C1CXCR1CXCR2KMT2A | |
| SCHEMBL31171007 | 0.80 | CXCR1 (0.62) | KCNMA1NR3C1CXCR1CXCR2KMT2A | |
| SCHEMBL2131627 | 0.80 | CXCR1 (0.62) | KCNMA1NR3C1CXCR1CXCR2KMT2A | |
| SCHEMBL5595104 | 0.80 | CXCR1 (0.80) | KCNMA1CXCR1CXCR2KMT2AMEN1 | |
| SCHEMBL17085327 | 0.78 | HTT (0.71) | KCNMA1NR3C1CXCR1CXCR2KMT2A | |
| SCHEMBL5987164 | 0.77 | CXCR1 (0.67) | KCNMA1NR3C1CXCR1CXCR2KMT2A | |
| SCHEMBL29968760 | 0.77 | CXCR1 (0.67) | KCNMA1NR3C1CXCR1CXCR2KMT2A | |
| SCHEMBL7859370 | 0.77 | CXCR1 (0.63) | KCNMA1NR3C1CXCR1CXCR2KMT2A | |
| SCHEMBL11358347 | 0.77 | CXCR1 (0.58) | KCNMA1NR3C1CXCR1CXCR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |