Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30949589 | 1.00 | GAA (0.51) | GAAKMT2AMEN1TDP1CXCR1 | |
| SCHEMBL23320439 | 0.82 | KCNMA1 (0.59) | GAAKMT2AMEN1TDP1CXCR1 | |
| SCHEMBL396053 | 0.81 | SMN1; SMN2 (0.57) | GAAKMT2AMEN1TDP1CXCR1 | |
| SCHEMBL30949559 | 0.80 | CETP (0.42) | GAAKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL30949560 | 0.80 | CETP (0.42) | GAAKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL2230525 | 0.79 | KMT2A (0.52) | GAAKMT2AMEN1TDP1CXCR1 | |
| SCHEMBL2230530 | 0.79 | KMT2A (0.52) | GAAKMT2AMEN1TDP1CXCR1 | |
| SCHEMBL2311747 | 0.78 | HTT (0.65) | GAAKMT2AMEN1TDP1CXCR1 | |
| SCHEMBL30661616 | 0.76 | KMT2A (0.47) | GAAKMT2AMEN1TDP1CXCR1 | |
| SCHEMBL2144447 | 0.76 | KMT2A (0.47) | GAAKMT2AMEN1TDP1CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652154-A1 | NOVEL ALPK1 INHIBITORS | Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153225-A1 | NOVEL ALPK1 INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |