Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 16/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320580 | 0.85 | NAMPT (0.59) | NAMPTHTTIMPDH2ROCK2ROCK1 | |
| SCHEMBL30943163 | 0.85 | NAMPT (0.59) | NAMPTHTTIMPDH2ROCK2ROCK1 | |
| SCHEMBL23320514 | 0.83 | NAMPT (0.55) | NAMPTHTTIMPDH2ROCK2ROCK1 | |
| SCHEMBL23320481 | 0.82 | NAMPT (0.57) | NAMPTHTTIMPDH2ROCK2ROCK1 | |
| SCHEMBL30943269 | 0.80 | NAMPT (0.54) | NAMPTHTTIMPDH2ROCK2ROCK1 | |
| SCHEMBL23320504 | 0.80 | NAMPT (0.54) | NAMPTHTTIMPDH2ROCK2ROCK1 | |
| SCHEMBL24042574 | 0.80 | NAMPT (0.54) | NAMPTHTTIMPDH2ROCK2ROCK1 | |
| SCHEMBL24042594 | 0.75 | NAMPT (0.51) | NAMPTHTTIMPDH2ROCK2ROCK1 | |
| SCHEMBL30943149 | 0.75 | NAMPT (0.51) | NAMPTHTTIMPDH2ROCK2ROCK1 | |
| SCHEMBL23320539 | 0.74 | PRMT3 (0.52) | NAMPTIMPDH2ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-A | Condensed ring compounds having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2021-04-13 | — | — | CN | claimed |
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |
| CN-112654608-A | Condensed ring compounds having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2021-04-13 | — | — | CN | disclosed |