SCHEMBL23320673

SCHEMBL23320673

Cc1sc2c(c1C)C(c1ccc(-c3ccc(O)cc3)cc1)=N[C@@H](C(C)C(=O)O)c1nnc(C)n1-2

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 20/20 0.56
BRD2 P25440 2/20 0.56
BRD3 Q15059 1/20 0.56
BRDT Q58F21 7/20 0.53
DNER Q8NFT8 1/20 0.53
ADORA3 P0DMS8 1/20 0.51
TSPO P30536 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2538202 0.94 BRD4 (0.52) BRD4BRD2BRD3BRDTDNER
SCHEMBL23320672 0.91 BRD4 (0.56) BRD4BRD2BRDTDNERADORA3
SCHEMBL2542128 0.91 BRD4 (0.53) BRD4BRD2BRD3BRDTDNER
SCHEMBL30320654 0.90 BRD4 (0.69) BRD4BRD2BRD3BRDTDNER
SCHEMBL2541331 0.90 BRD4 (0.57) BRD4BRD2BRDTDNERADORA3
SCHEMBL2541813 0.90 BRD4 (0.69) BRD4BRD2BRD3BRDTDNER
SCHEMBL2541333 0.90 BRD4 (0.57) BRD4BRD2BRDTDNERADORA3
SCHEMBL2541816 0.90 BRD4 (0.69) BRD4BRD2BRD3BRDTDNER
SCHEMBL23320754 0.90 BRD4 (0.51) BRD4BRD2BRD3BRDTDNER
SCHEMBL2535198 0.90 BRD4 (0.55) BRD4BRD2BRD3BRDTDNER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3819305-A1 AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF Mitsubishi Tanabe Pharma Corporation (JP) 2021-05-12 EP disclosed