Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.51 |
| ▸ | BRD2 | P25440 | 3/20 | 0.51 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.51 |
| ▸ | BRDT | Q58F21 | 5/20 | 0.49 |
| ▸ | DNER | Q8NFT8 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23321451 | 0.92 | BRD4 (0.49) | BRD4BRD2BRD3BRDTDNER | |
| SCHEMBL23321048 | 0.92 | BRD4 (0.53) | BRD4BRD2BRD3BRDTDNER | |
| SCHEMBL23320673 | 0.90 | BRD4 (0.56) | BRD4BRD2BRD3BRDTDNER | |
| SCHEMBL2542128 | 0.87 | BRD4 (0.53) | BRD4BRD2BRD3BRDTDNER | |
| SCHEMBL2538202 | 0.86 | BRD4 (0.52) | BRD4BRD2BRD3BRDTDNER | |
| SCHEMBL2541813 | 0.85 | BRD4 (0.69) | BRD4BRD2BRD3BRDTDNER | |
| SCHEMBL2541816 | 0.85 | BRD4 (0.69) | BRD4BRD2BRD3BRDTDNER | |
| SCHEMBL2541333 | 0.85 | BRD4 (0.57) | BRD4BRD2BRDTDNERADORA3 | |
| SCHEMBL30320654 | 0.85 | BRD4 (0.69) | BRD4BRD2BRD3BRDTDNER | |
| SCHEMBL23320672 | 0.84 | BRD4 (0.56) | BRD4BRD2BRDTDNERADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3819305-A1 | AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2021-05-12 | — | — | EP | disclosed |