Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23321704 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23321609 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23322177 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23321855 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23321911 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23321741 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23321867 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23321719 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23321940 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23322075 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240409563-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. | 2024-12-12 | — | — | US | claimed |
| EP-4448536-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. (US) | 2024-10-23 | — | — | EP | claimed |
| CN-118401532-A | High-purity polysiloxane macromer and preparation method thereof | 盖列斯特有限公司 | 2024-07-26 | — | — | CN | claimed |
| WO-2023113779-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. (US) | 2023-06-22 | — | — | WO | claimed |
| US-20230183273-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. | 2023-06-15 | — | — | US | claimed |
| US-20240409563-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. | 2024-12-12 | — | — | US | disclosed |
| EP-4448536-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. (US) | 2024-10-23 | — | — | EP | disclosed |
| CN-118401532-A | High-purity polysiloxane macromer and preparation method thereof | 盖列斯特有限公司 | 2024-07-26 | — | — | CN | disclosed |
| WO-2023113779-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| US-20230183273-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. | 2023-06-15 | — | — | US | disclosed |
| US-11377455-B2 | Preparation of organosilicon compound having (meth)acryloyloxy group | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-07-05 | — | — | US | disclosed |
| US-20210139515-A1 | Preparation of Organosilicon Compound Having (Meth)acryloyloxy Group | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-05-13 | — | — | US | disclosed |
| EP-3819301-A1 | PREPARATION OF ORGANOSILICON COMPOUND HAVING (METH)ACRYLOYLOXY GROUP | Shin-Etsu Chemical Co., Ltd. (JP) | 2021-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409563-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | SSRP1, RPLP2, RPLP1 | TSHR 1897/4885POLB 307/4885APEX1 404/4885 |
| US-11377455-B2 | Preparation of organosilicon compound having (meth)acryloyloxy group | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MMAB, ACR | TSHR 1239/4885POLB 1464/4885APEX1 180/4885 |
| US-20230183273-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | SSRP1, RPLP2, RPLP1 | TSHR 1897/4885POLB 307/4885APEX1 404/4885 |
| US-20210139515-A1 | Preparation of Organosilicon Compound Having (Meth)acryloyloxy Group | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MMAB, ACR | TSHR 1250/4885POLB 1427/4885APEX1 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.