SCHEMBL23322237

SCHEMBL23322237

C=CC(=O)OCCCCC([SiH3])(Cl)Cl

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.62
ALDH1A1 P00352 4/20 0.62
CYP3A4 P08684 2/20 0.62
HPGD P15428 1/20 0.52
TP53 P04637 3/20 0.47
HIF1A Q16665 3/20 0.47
HSD17B10 Q99714 1/20 0.47
THRB P10828 2/20 0.40
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ATM Q13315 1/20 0.33
HCAR2 Q8TDS4 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23322190 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23322147 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23322148 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23322206 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23321637 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23321831 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23321514 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23321699 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23321641 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23322162 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3819301-B1 PREPARATION OF ORGANOSILICON COMPOUND HAVING (METH)ACRYLOYLOXY GROUP SHINETSU CHEMICAL CO (JP) 2025-08-06 EP disclosed
US-11377455-B2 Preparation of organosilicon compound having (meth)acryloyloxy group SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-07-05 US disclosed
US-20210139515-A1 Preparation of Organosilicon Compound Having (Meth)acryloyloxy Group SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-05-13 US disclosed
EP-3819301-A1 PREPARATION OF ORGANOSILICON COMPOUND HAVING (METH)ACRYLOYLOXY GROUP Shin-Etsu Chemical Co., Ltd. (JP) 2021-05-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11377455-B2 Preparation of organosilicon compound having (meth)acryloyloxy group H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MMAB, ACR TSHR 1239/4885ALDH1A1 2631/4885CYP3A4 2331/4885
US-20210139515-A1 Preparation of Organosilicon Compound Having (Meth)acryloyloxy Group H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MMAB, ACR TSHR 1250/4885ALDH1A1 2744/4885CYP3A4 2392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.