SCHEMBL23322790

SCHEMBL23322790

O=C1C(=Cc2ccc(N3c4ccccc4Sc4cc(F)ccc43)s2)C(=O)c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.43
MAPT P10636 5/20 0.43
ALDH1A1 P00352 4/20 0.43
HPGD P15428 3/20 0.43
NPSR1 Q6W5P4 3/20 0.43
THRB P10828 1/20 0.43
RECQL P46063 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HTT P42858 1/20 0.36
MEN1 O00255 4/20 0.34
POLB P06746 4/20 0.34
SMN1; SMN2 Q16637 4/20 0.34
NFKB1 P19838 2/20 0.34
NFKB2 Q00653 2/20 0.34
RELA Q04206 2/20 0.34
NPC1 O15118 1/20 0.34
HCRTR1 O43613 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23322789 0.93 MAPT (0.43) KMT2AMAPTALDH1A1HPGDNPSR1
SCHEMBL23322658 0.93 NPSR1 (0.36) KMT2AMAPTALDH1A1HPGDNPSR1
SCHEMBL19603584 0.89 MAPT (0.52) KMT2AMAPTALDH1A1HPGDNPSR1
SCHEMBL23322718 0.86 ALDH1A1 (0.32) KMT2AMAPTALDH1A1HPGDNPSR1
SCHEMBL23322655 0.86 NPSR1 (0.36) KMT2AMAPTALDH1A1HPGDNPSR1
SCHEMBL23322735 0.85 PRF1 (0.37) KMT2AMAPTALDH1A1HPGDNPSR1
SCHEMBL19603567 0.82 KMT2A (0.42) KMT2AMAPTALDH1A1HPGDNPSR1
SCHEMBL23322717 0.80 ALDH1A1 (0.32) KMT2AMAPTALDH1A1HPGDNPSR1
SCHEMBL23323021 0.80 KMT2A (0.43) KMT2AMAPTALDH1A1HPGDNPSR1
SCHEMBL23322715 0.80 KMT2A (0.43) KMT2AMAPTALDH1A1HPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793007-B2 Photoelectric conversion devices and sensors and electronic devices SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-10-17 US disclosed
US-20210135136-A1 PHOTOELECTRIC CONVERSION DEVICES AND SENSORS AND ELECTRONIC DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-05-06 US disclosed