Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507844 | 0.82 | TSHR (0.42) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL2648364 | 0.82 | TSHR (0.42) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL14602695 | 0.78 | TSHR (0.39) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL10010416 | 0.78 | TSHR (0.39) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL14639582 | 0.77 | TSHR (0.37) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL11847482 | 0.77 | TSHR (0.37) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL10012251 | 0.77 | MGAM (0.39) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL27992948 | 0.77 | MGAM (0.39) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL10025765 | 0.77 | TSHR (0.37) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL10012505 | 0.77 | MGAM (0.39) | TSHRMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523313-B1 | DIBENZO[D,B]SILOLE-BASED REACTIVE MESOGENS | LOMOX LTD (GB) | 2021-05-05 | — | — | EP | disclosed |