Sugi Predict

Sugi Predict / Compounds / SCHEMBL5507844

SCHEMBL5507844

SCHEMBL5507844

COC(=O)CC(OC)C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 4/20 0.42
▸ MGAM O43451 2/20 0.39
▸ GAA P10253 2/20 0.39
▸ SI P14410 2/20 0.39
▸ MGAM2 Q2M2H8 2/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ CA14 Q9ULX7 2/20 0.32
▸ TET2 Q6N021 1/20 0.32
▸ ABCB1 P08183 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ ZDHHC7 Q9NXF8 1/20 0.31
▸ CA12 O43570 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2648364 1.00 TSHR (0.42) TSHRMGAMGAASIMGAM2
SCHEMBL24242168 0.85 GAA (0.50) TSHRMGAMGAASIMGAM2
SCHEMBL14602695 0.82 TSHR (0.39) TSHRMGAMGAASIMGAM2
SCHEMBL10010416 0.82 TSHR (0.39) TSHRMGAMGAASIMGAM2
SCHEMBL23323136 0.82 TSHR (0.39) TSHRMGAMGAASIMGAM2
SCHEMBL24242061 0.81 CYP2D6 (0.42) GAASMN1; SMN2KMT2AMEN1CA1
SCHEMBL2646187 0.81 PARP1 (0.40) TSHRSMN1; SMN2KMT2ACA1CA2
SCHEMBL13345390 0.81 TSHR (0.42) TSHRMGAMGAASIMGAM2
SCHEMBL10404573 0.81 PARP1 (0.40) TSHRSMN1; SMN2KMT2ACA1CA2
SCHEMBL10012251 0.80 MGAM (0.39) TSHRMGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479831-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME Ube Industries, Ltd. (JP) 2012-07-25 — — EP claimed
US-20120171581-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME UBE INDUSTRIES, LTD. (JP) 2012-07-05 — — US claimed
CN-101107071-B Hydroprocessing catalyst, preparation method thereof and use of same TOTAL FRANCE 2011-05-18 — — CN claimed
CN-101107071-A Hydroprocessing catalyst, preparation method thereof and use of same TOTAL FRANCE (FR) 2008-01-16 — — CN claimed
EP-3728235-B1 SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2022-02-09 — — EP disclosed
CN-113200853-A Process method for preparing butanediol succinate 宁波窦氏化学科技有限公司 2021-08-03 — — CN disclosed
WO-2019069270-A1 MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2019-04-11 — — WO disclosed
US-20170283362-A9 Process For The Production Of Dialkyl Succinate From Maleic Anyhdride JOHNSON MATTHEY DAVY TECHNOLOGIES LIMITED (GB) 2017-10-05 — — US disclosed
US-9776947-B2 Process for the production of dialkyl succinate from maleic anyhdride JOHNSON MATTHEY DAVY TECHNOLOGIES LIMITED (GB) 2017-10-03 — — US disclosed
EP-2885268-B1 PROCESS FOR THE PREPARATION OF DIALKYL SUCCINATE FROM MALEIC ANHYDRIDE JOHNSON MATTHEY DAVY TECHNOLOGIES LTD (GB) 2017-07-26 — — EP disclosed
US-9464261-B2 Polymer-containing cleaning compositions and methods of production and use thereof THE SUN PRODUCTS CORPORATION (US) 2016-10-11 — — US disclosed
US-20160214922-A1 Process For The Production Of Dialkyl Succinate From Maleic Anyhdride JOHNSON MATTHEY DAVY TECHNOLOGIES LTD (GB) 2016-07-28 — — US disclosed
WO-1997025452-A1 PROCESS FOR THE PREPARATION OF TETRAALKYL 1,2,3,4-BUTANETETRACARBOXYLATES MONSANTO COMPANY (US) 1997-07-17 — — WO disclosed
US-5364964-A Hydrolyzing the tetramethyl ester; methanol distillation; oxidation with hydrogen peroxide; discoloration inhibition MONSANTO COMPANY (US) 1994-11-15 — — US disclosed
US-5298653-A Hydrolysis of ester using acid catalyst; using hydrogen peroxide to remove color impurities MONSANTO COMPANY (US) 1994-03-29 — — US disclosed
US-5248396-A Hydrodimerization of dialkyl maleate MONSANTO COMPANY (US) 1993-09-28 — — US disclosed
US-5244546-A Process for preparing tetraalkyl butanetetracarboxylates MONSANTO COMPANY (US) 1993-09-14 — — US disclosed
CN-1052514-A The preparation method of butanetetra-carboxylic acid MONSANTO CO (US) 1991-06-26 — — CN disclosed
EP-0433260-A2 Process for preparing butanetetracarboxylic acid MONSANTO COMPANY (US) 1991-06-19 — — EP disclosed
US-4460782-A FUNGICIDES CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1984-07-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160214922-A1 Process For The Production Of Dialkyl Succinate From Maleic Anyhdride SORD, HADH, HADHA TSHR 4453/4885MGAM 120/4885GAA 628/4885
US-20170283362-A9 Process For The Production Of Dialkyl Succinate From Maleic Anyhdride SORD, HADH, HADHA TSHR 4453/4885MGAM 120/4885GAA 628/4885
US-20120171581-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME SLC8A1, OR10J3, SLC8B1 TSHR 3669/4885MGAM 4087/4885GAA 4655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.