Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23323125 | 1.00 | SLC6A4 (0.31) | SLC6A4SLC6A3PIM1 | |
| SCHEMBL24854060 | 0.81 | LRRK2 (0.30) | — | |
| SCHEMBL24775170 | 0.81 | LRRK2 (0.30) | — | |
| SCHEMBL24775798 | 0.80 | SAT1 (0.38) | — | |
| SCHEMBL24737240 | 0.80 | NR1H2 (0.31) | — | |
| SCHEMBL23177943 | 0.78 | KDM4E (0.36) | — | |
| SCHEMBL13279878 | 0.75 | ESR2 (0.34) | SLC6A4SLC6A3 | |
| SCHEMBL17682168 | 0.75 | APLNR (0.36) | PIM1 | |
| SCHEMBL23487505 | 0.75 | ESR2 (0.34) | SLC6A4SLC6A3 | |
| SCHEMBL25025847 | 0.74 | FFAR4 (0.35) | PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021208963-A1 | BCL-2 INHIBITOR | BEIGENE, LTD. (KY) | 2021-10-21 | — | — | WO | disclosed |
| WO-2021083135-A1 | Bcl-2 INHIBITORS | BEIGENE, LTD. (KY) | 2021-05-06 | — | — | WO | disclosed |