Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28740958 | 0.95 | IKBKB (0.45) | HCRTR2CHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL27837299 | 0.87 | KDM1A (0.39) | HCRTR2CHRNB2CHRNA4KMT2AKDM1A | |
| SCHEMBL23323109 | 0.83 | CHRM5 (0.41) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| Hydrochloric Acid SCHEMBL29747942 | 0.79 | MEN1 (0.39) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL15880395 | 0.78 | MEN1 (0.41) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL2859123 | 0.78 | HTR2C (0.43) | HCRTR2KDM1A | |
| SCHEMBL28986744 | 0.76 | ADRA1A (0.33) | HCRTR2KDM1A | |
| SCHEMBL31525053 | 0.74 | MEN1 (0.38) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL24737036 | 0.74 | MEN1 (0.38) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL23323069 | 0.74 | CHRM5 (0.46) | CHRM5CHRM3CHRM2CHRM1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021083135-A1 | Bcl-2 INHIBITORS | BEIGENE, LTD. (KY) | 2021-05-06 | — | — | WO | disclosed |