Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27324183 | 0.82 | — | — | |
| SCHEMBL13444989 | 0.70 | TDP1 (0.45) | BCHEDPP4 | |
| SCHEMBL23324916 | 0.69 | BCHE (0.38) | BCHEDPP4HTR1A | |
| SCHEMBL29294175 | 0.69 | DPP4 (0.35) | BCHEDPP4 | |
| SCHEMBL23325918 | 0.68 | BCHE (0.31) | BCHE | |
| SCHEMBL7677403 | 0.67 | GRM2 (0.35) | BCHEDPP4 | |
| SCHEMBL23325441 | 0.63 | BCHE (0.34) | BCHEDPP4 | |
| SCHEMBL25953036 | 0.62 | BCHE (0.33) | BCHEDPP4 | |
| SCHEMBL18959507 | 0.62 | BCHE (0.55) | BCHEDPP4 | |
| SCHEMBL27324185 | 0.62 | BCHE (0.55) | BCHEDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11566007-B2 | Ras inhibitors | Revolution Medicines, Inc. (US) | 2023-01-31 | — | — | US | disclosed |
| US-20210130303-A1 | RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11566007-B2 | Ras inhibitors | KRAS, NRAS, HRAS | BCHE 4352/4885DPP4 2889/4885HTR1A 4804/4885 |
| US-20210130303-A1 | RAS INHIBITORS | KRAS, NRAS, HRAS | BCHE 4352/4885DPP4 2889/4885HTR1A 4804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.