Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 10/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4149003 | 0.79 | TBXA2R (0.44) | BACE1TBXA2RNR1H2KMT2A | |
| SCHEMBL6221657 | 0.78 | TBXA2R (0.47) | BACE1TBXA2RNR1H2KMT2A | |
| SCHEMBL22955468 | 0.77 | TBXA2R (0.41) | BACE1TBXA2RNR1H2KMT2A | |
| SCHEMBL6262451 | 0.70 | ALOX5AP (0.46) | BACE1 | |
| SCHEMBL6737502 | 0.70 | BRD4 (0.42) | LMNAADORA2ANR1H2KMT2A | |
| SCHEMBL1283797 | 0.69 | PIK3CA (0.41) | TBXA2R | |
| SCHEMBL29594722 | 0.69 | HSP90AA1 (0.39) | LMNANR1H2KMT2A | |
| SCHEMBL20915779 | 0.69 | HSP90AA1 (0.39) | LMNANR1H2KMT2A | |
| SCHEMBL6224033 | 0.68 | BRD4 (0.44) | TBXA2RADORA2A | |
| SCHEMBL30828711 | 0.68 | BRD4 (0.44) | TBXA2RADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771441-B1 | NOVEL CARBOXAMIDES FOR USE AS XA INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2011-08-17 | — | — | EP | disclosed |