SCHEMBL23327151

SCHEMBL23327151

O=CCC12CCC(C(=O)O)(CC1)C2

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21542429 0.77 CHRM1 (0.35)
SCHEMBL31116092 0.76 ALDH1A1 (0.33) ALDH1A1
SCHEMBL19614682 0.74 GRM1 (0.34) ALDH1A1
SCHEMBL10210793 0.74 ALDH1A1 (0.35) ALDH1A1
SCHEMBL21542371 0.74 ALDH1A1 (0.32) ALDH1A1
SCHEMBL16700084 0.74 ALDH1A1 (0.32) ALDH1A1
SCHEMBL23327561 0.73 CYP4F2 (0.32)
SCHEMBL478303 0.71 GRM1 (0.40)
SCHEMBL4036460 0.69 ALDH1A1 (0.33) ALDH1A1
SCHEMBL10160156 0.69 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240132523-A1 SALTS AND CRYSTALLINE FORMS OF A PD-1/PD-L1 INHIBITOR INCYTE CORPORATION 2024-04-25 US claimed
CN-114829366-A Salts and crystalline forms of PD-1/PD-L1 inhibitors 因赛特公司 2022-07-29 CN claimed
WO-2021096849-A1 SALTS AND CRYSTALLINE FORMS OF A PD-1/PD-L1 INHIBITOR INCYTE CORPORATION (US) 2021-05-20 WO claimed
US-20210139511-A1 SALTS AND CRYSTALLINE FORMS OF A PD-1/PD-L1 INHIBITOR INCYTE CORPORATION 2021-05-13 US claimed
US-20240132523-A1 SALTS AND CRYSTALLINE FORMS OF A PD-1/PD-L1 INHIBITOR INCYTE CORPORATION 2024-04-25 US disclosed
WO-2024018403-A1 SUBSTITUTED IMIDAZOAMIDE COMPOUNDS, AND METHODS USING SAME ARBUTUS BIOPHARMA CORPORATION (CA) 2024-01-25 WO disclosed
US-11866451-B2 Salts and crystalline forms of a PD-1/PD-L1 inhibitor INCYTE CORPORATION (US) 2024-01-09 US disclosed
WO-2022161421-A1 BIPHENYL COMPOUND AS IMMUNOMODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 深圳微芯生物科技股份有限公司 2022-08-04 WO disclosed
CN-114829366-A Salts and crystalline forms of PD-1/PD-L1 inhibitors 因赛特公司 2022-07-29 CN disclosed
WO-2022089511-A1 BIPHENYL COMPOUND AS IMMUNOMODULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 深圳微芯生物科技股份有限公司 2022-05-05 WO disclosed
WO-2021139647-A1 BIPHENYL FLUORINE DOUBLE BOND DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF 上海和誉生物医药科技有限公司 2021-07-15 WO disclosed
WO-2021096849-A1 SALTS AND CRYSTALLINE FORMS OF A PD-1/PD-L1 INHIBITOR INCYTE CORPORATION (US) 2021-05-20 WO disclosed
WO-2021096849-A1 SALTS AND CRYSTALLINE FORMS OF A PD-1/PD-L1 INHIBITOR INCYTE CORPORATION (US) 2021-05-20 WO disclosed
US-20210139511-A1 SALTS AND CRYSTALLINE FORMS OF A PD-1/PD-L1 INHIBITOR INCYTE CORPORATION 2021-05-13 US disclosed
US-20210139511-A1 SALTS AND CRYSTALLINE FORMS OF A PD-1/PD-L1 INHIBITOR INCYTE CORPORATION 2021-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132523-A1 SALTS AND CRYSTALLINE FORMS OF A PD-1/PD-L1 INHIBITOR CD274, PDCD1, PDCD1LG2 ALDH1A1 295/4885
US-11866451-B2 Salts and crystalline forms of a PD-1/PD-L1 inhibitor CD274, PDCD1, PDCD1LG2 ALDH1A1 295/4885
US-20210139511-A1 SALTS AND CRYSTALLINE FORMS OF A PD-1/PD-L1 INHIBITOR CD274, PDCD1, PDCD1LG2 ALDH1A1 295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.