Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21719705 | 0.83 | — | — | |
| SCHEMBL9429829 | 0.78 | POLB (0.36) | POLBLMNAKMT2ANPC1PKM | |
| SCHEMBL13551126 | 0.77 | KMT2A (0.40) | POLBLMNAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL12160719 | 0.76 | POLB (0.37) | POLBLMNAKMT2AMPOSMN1; SMN2 | |
| SCHEMBL21720954 | 0.75 | — | — | |
| SCHEMBL18116896 | 0.74 | POLB (0.43) | POLBLMNAKMT2AMPOSMN1; SMN2 | |
| SCHEMBL24677367 | 0.74 | ESR1 (0.30) | — | |
| SCHEMBL24677207 | 0.74 | POLB (0.37) | POLBLMNAKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL24677205 | 0.74 | BRD9 (0.30) | — | |
| SCHEMBL12546378 | 0.72 | POLB (0.35) | POLBLMNAKMT2AMPOSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4052576-A1 | AMIDE COMPOUND CONTAINING SUBSTITUTED ACETOPHENONE STRUCTURE FRAGMENT, PREPARATION METHOD THEREFOR AND USE THEREOF | Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) | 2022-09-07 | — | — | EP | disclosed |
| WO-2021082997-A1 | AMIDE COMPOUND CONTAINING SUBSTITUTED ACETOPHENONE STRUCTURE FRAGMENT, PREPARATION METHOD THEREFOR AND USE THEREOF | 沈阳中化农药化工研发有限公司 | 2021-05-06 | — | — | WO | disclosed |