Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23328193 | 0.78 | POLB (0.38) | POLBKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23328197 | 0.74 | POLB (0.36) | POLBKMT2ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL9429829 | 0.74 | POLB (0.36) | POLBKMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL13551126 | 0.72 | KMT2A (0.40) | POLBKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL24677206 | 0.67 | L3MBTL1 (0.38) | POLBCYP1A2CYP2D6SMN1; SMN2L3MBTL1 | |
| SCHEMBL12673219 | 0.65 | POLB (0.36) | POLBKMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL15941912 | 0.65 | POLB (0.47) | POLBKMT2ALMNAGABRPGABRD | |
| SCHEMBL15942091 | 0.65 | KMT2A (0.38) | POLBKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21863292 | 0.64 | POLB (0.35) | POLBKMT2ALMNAL3MBTL1 | |
| SCHEMBL15942034 | 0.61 | PKM (0.37) | POLBKMT2ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4052576-A1 | AMIDE COMPOUND CONTAINING SUBSTITUTED ACETOPHENONE STRUCTURE FRAGMENT, PREPARATION METHOD THEREFOR AND USE THEREOF | Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) | 2022-09-07 | — | — | EP | disclosed |