Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 10/20 | 0.39 |
| ▸ | KDR | P35968 | 10/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23328332 | 0.89 | FGFR1 (0.41) | FGFR1FGFR4KDR | |
| SCHEMBL23328715 | 0.83 | FGFR1 (0.38) | FGFR1FGFR4KDRFGFR2 | |
| SCHEMBL23328287 | 0.82 | FGFR1 (0.55) | FGFR1FGFR4KDRFGFR2FGFR3 | |
| SCHEMBL23328264 | 0.82 | FGFR1 (0.42) | FGFR1FGFR4KDR | |
| SCHEMBL23328282 | 0.81 | FGFR1 (0.53) | FGFR1FGFR4KDRFGFR2 | |
| SCHEMBL29545722 | 0.81 | FGFR2 (0.51) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL20733997 | 0.81 | FGFR2 (0.51) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL20733929 | 0.76 | FGFR1 (0.37) | FGFR1FGFR4KDRFGFR2 | |
| SCHEMBL29545761 | 0.76 | FGFR1 (0.37) | FGFR1FGFR4KDRFGFR2 | |
| SCHEMBL31344339 | 0.71 | CA12 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365196-B2 | FGFR inhibitor and application thereof | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2022-06-21 | — | — | US | disclosed |
| US-20210130353-A1 | FGFR INHIBITOR AND APPLICATION THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365196-B2 | FGFR inhibitor and application thereof | FGFR1, FGFR4, FGFR2 | FGFR1 1/4885FGFR4 2/4885KDR 12/4885 |
| US-20210130353-A1 | FGFR INHIBITOR AND APPLICATION THEREOF | FGFR1, FGFR4, FGFR2 | FGFR1 1/4885FGFR4 2/4885KDR 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.