SCHEMBL20733929 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	FGFR1	P11362	18/20	0.37

▸	MEN1	O00255	1/20	0.37

▸	NPC1	O15118	1/20	0.37

▸	RAB9A	P51151	1/20	0.37

▸	KMT2A	Q03164	1/20	0.37

▸	TLR9	Q9NR96	1/20	0.37

▸	FGFR4	P22455	8/20	0.36

▸	KDR	P35968	7/20	0.36

▸	FGFR2	P21802	6/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29545761	1.00	FGFR1 (0.37)	FGFR1MEN1NPC1RAB9AKMT2A
SCHEMBL16072024	0.86	FGFR4 (0.42)	FGFR1MEN1NPC1RAB9AKMT2A
SCHEMBL20733930	0.84	FGFR1 (0.44)	FGFR1FGFR4KDRFGFR2
SCHEMBL20734006	0.82	FGFR1 (0.40)	FGFR1MEN1NPC1RAB9AKMT2A
SCHEMBL29545714	0.82	FGFR1 (0.40)	FGFR1MEN1NPC1RAB9AKMT2A
SCHEMBL29545501	0.82	FGFR1 (0.38)	FGFR1MEN1KMT2AFGFR4KDR
SCHEMBL16246296	0.82	FGFR1 (0.38)	FGFR1MEN1KMT2AFGFR4KDR
SCHEMBL29546028	0.80	FGFR4 (0.39)	FGFR1FGFR4KDRFGFR2
SCHEMBL20733932	0.80	FGFR1 (0.36)	FGFR1FGFR4KDRFGFR2
SCHEMBL29546202	0.80	FGFR1 (0.36)	FGFR1FGFR4KDRFGFR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019029541-A1	FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITOR AND USE THEREOF	南京药捷安康生物科技有限公司	2019-02-14	—	—	WO	disclosed