Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23300648 | 1.00 | EPHX2 (0.38) | EPHX2NFKB1NFKB2RELAKDM1A | |
| SCHEMBL31289638 | 1.00 | EPHX2 (0.38) | EPHX2NFKB1NFKB2RELAKDM1A | |
| SCHEMBL23300683 | 1.00 | EPHX2 (0.38) | EPHX2NFKB1NFKB2RELAKDM1A | |
| SCHEMBL23300625 | 0.90 | EPHX2 (0.37) | EPHX2NFKB1NFKB2RELAKDM1A | |
| SCHEMBL31289640 | 0.90 | EPHX2 (0.37) | EPHX2NFKB1NFKB2RELAKDM1A | |
| SCHEMBL29823637 | 0.83 | EPHX2 (0.33) | EPHX2NFKB1NFKB2RELAKDM1A | |
| SCHEMBL23300665 | 0.83 | — | — | |
| SCHEMBL23300668 | 0.83 | — | — | |
| SCHEMBL23328843 | 0.79 | KDM1A (0.42) | EPHX2NFKB1NFKB2RELAKDM1A | |
| SCHEMBL23328809 | 0.79 | KDM1A (0.42) | EPHX2NFKB1NFKB2RELAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021083011-A1 | BRIDGED CYCLOFORMYLPYRIDINE DERIVATIVE AND USE THEREOF | 北京伯汇生物技术有限公司 | 2021-05-06 | — | — | WO | disclosed |