Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23328843 | 1.00 | KDM1A (0.42) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL29874561 | 0.82 | PIK3CD (0.40) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL23328801 | 0.79 | EPHX2 (0.38) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL31289638 | 0.79 | EPHX2 (0.38) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL23300683 | 0.79 | EPHX2 (0.38) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL23300648 | 0.79 | EPHX2 (0.38) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL31289640 | 0.78 | EPHX2 (0.37) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL23300625 | 0.78 | EPHX2 (0.37) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL19297333 | 0.72 | KDM1A (0.48) | KDM1AMAOBKMT2AL3MBTL1EPHX2 | |
| SCHEMBL24742006 | 0.72 | KMT2A (0.43) | KDM1AMAOBKMT2AL3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021083011-A1 | BRIDGED CYCLOFORMYLPYRIDINE DERIVATIVE AND USE THEREOF | 北京伯汇生物技术有限公司 | 2021-05-06 | — | — | WO | disclosed |