Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.52 |
| ▸ | CTSK | P43235 | 5/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22883188 | 0.85 | CTSS (0.57) | CTSSCTSKKLK5ATMPPARA | |
| SCHEMBL23419514 | 0.81 | AAK1 (0.47) | CTSSCTSKKLK5ATMPPARA | |
| SCHEMBL6158011 | 0.81 | CTSS (0.53) | CTSSCTSKKLK5ATMCTSL | |
| SCHEMBL21669247 | 0.79 | PPARG (0.46) | CTSSCTSKKLK5ATMPPARA | |
| SCHEMBL7422441 | 0.78 | CTSS (0.56) | CTSSCTSKKLK5ATMPPARA | |
| SCHEMBL21669235 | 0.78 | PPARG (0.45) | KLK5ATMPPARAPPARGITGB3 | |
| SCHEMBL13617752 | 0.77 | KLK5 (0.49) | CTSSCTSKKLK5ATM | |
| SCHEMBL13446081 | 0.77 | CTSS (0.60) | CTSSCTSKATMPPARAMIF | |
| SCHEMBL8543180 | 0.77 | CTSS (0.60) | CTSSCTSKATMPPARAMIF | |
| SCHEMBL920111 | 0.77 | CTSS (0.63) | CTSSCTSKKLK5CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021086133-A1 | TRICYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF | (주)제이디바이오사이언스 | 2021-05-06 | — | — | WO | disclosed |