SCHEMBL23329308

SCHEMBL23329308

CCCCc1ccc2oc(=O)ccc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 0.61
CA9 Q16790 7/20 0.61
CA2 P00918 6/20 0.61
CA3 P07451 6/20 0.61
CA4 P22748 6/20 0.61
CA7 P43166 6/20 0.61
CA14 Q9ULX7 6/20 0.61
CA5B Q9Y2D0 6/20 0.61
CA6 P23280 5/20 0.61
CA5A P35218 5/20 0.61
CA1 P00915 5/20 0.61
ALDH1A1 P00352 4/20 0.53
KDM4E B2RXH2 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
CYP2A6 P11509 1/20 0.49
MCL1 Q07820 1/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
CYP19A1 P11511 1/20 0.48
GMNN O75496 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21657215 0.90 CA12 (0.65) CA12CA9CA2CA3CA4
SCHEMBL8750141 0.83 CA12 (0.69) CA12CA9CA2CA3CA4
SCHEMBL30843838 0.80 CA12 (0.75) CA12CA9CA2CA3CA4
SCHEMBL4927952 0.80 CA12 (0.75) CA12CA9CA2CA3CA4
SCHEMBL18823325 0.79 CA12 (0.63) CA12CA9CA2CA3CA4
SCHEMBL1491019 0.78 CA9 (0.62) CA12CA9CA2CA3CA4
SCHEMBL13904858 0.78 CA12 (0.68) CA12CA9CA2CA3CA4
SCHEMBL1537772 0.76 SKP2 (0.55) CA2CA1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL31593167 0.76 SKP2 (0.55) CA2CA1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL13073997 0.76 CA9 (0.80) CA12CA9CA2CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11833493-B2 Metal catalyst, method of C-N coupling using the same and applications of the same BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2023-12-05 US disclosed
US-11376576-B2 Metal catalyst, method of C—N coupling using the same and applications of the same BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2022-07-05 US disclosed
US-20210129123-A1 METAL CATALYST, METHOD OF C-N COUPLING USING THE SAME AND APPLICATIONS OF THE SAME BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS 2021-05-06 US disclosed