Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 0.75 |
| ▸ | CA9 | Q16790 | 9/20 | 0.75 |
| ▸ | CA2 | P00918 | 5/20 | 0.75 |
| ▸ | CA3 | P07451 | 5/20 | 0.75 |
| ▸ | CA4 | P22748 | 5/20 | 0.75 |
| ▸ | CA5A | P35218 | 5/20 | 0.75 |
| ▸ | CA7 | P43166 | 5/20 | 0.75 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.75 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.75 |
| ▸ | CA6 | P23280 | 4/20 | 0.75 |
| ▸ | CA1 | P00915 | 5/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30843838 | 1.00 | CA12 (0.75) | CA12CA9CA2CA3CA4 | |
| SCHEMBL5904495 | 0.88 | CA12 (0.68) | CA12CA9CA2CA3CA4 | |
| SCHEMBL10350668 | 0.86 | CA12 (1.00) | CA12CA9CA2CA3CA4 | |
| SCHEMBL21657215 | 0.83 | CA12 (0.65) | CA12CA9CA2CA3CA4 | |
| SCHEMBL1491019 | 0.81 | CA9 (0.62) | CA12CA9CA2CA3CA4 | |
| SCHEMBL23329308 | 0.80 | CA12 (0.61) | CA12CA9CA2CA3CA4 | |
| SCHEMBL8750141 | 0.79 | CA12 (0.69) | CA12CA9CA2CA3CA4 | |
| SCHEMBL31741273 | 0.79 | CA12 (0.69) | CA12CA9CA2CA3CA4 | |
| SCHEMBL28776384 | 0.79 | CA12 (1.00) | CA12CA9CA2CA3CA4 | |
| SCHEMBL3663606 | 0.79 | CA12 (0.69) | CA12CA9CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2008-08-14 | — | — | US | disclosed |
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2008-08-14 | — | — | US | disclosed |
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | MAOA, MAOB, COMT | CA12 3628/4885CA9 2007/4885CA2 3212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.