Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPEPLD | Q6IQ20 | 9/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23304367 | 0.91 | NAPEPLD (0.39) | NAPEPLDEHMT2EHMT1 | |
| SCHEMBL23684701 | 0.87 | NAPEPLD (0.36) | NAPEPLDEHMT2EHMT1 | |
| SCHEMBL23304386 | 0.84 | PIK3CA (0.40) | NAPEPLDEHMT2EHMT1 | |
| SCHEMBL23304406 | 0.81 | EHMT2 (0.36) | NAPEPLDEHMT2EHMT1 | |
| SCHEMBL23329882 | 0.78 | NAPEPLD (0.37) | NAPEPLD | |
| SCHEMBL23684473 | 0.76 | EHMT2 (0.34) | NAPEPLDEHMT2EHMT1 | |
| SCHEMBL25062941 | 0.76 | NAPEPLD (0.39) | NAPEPLD | |
| SCHEMBL23304427 | 0.75 | NAPEPLD (0.39) | NAPEPLDEHMT2EHMT1 | |
| SCHEMBL17303810 | 0.73 | HCRTR1 (0.37) | EHMT2EHMT1 | |
| SCHEMBL25063004 | 0.73 | NAPEPLD (0.40) | NAPEPLDEHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021086879-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2021-05-06 | — | — | WO | disclosed |