Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 9/20 | 0.76 |
| ▸ | ADRA2A | P08913 | 8/20 | 0.76 |
| ▸ | ADRA2B | P18089 | 8/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.76 |
| ▸ | LMNA | P02545 | 4/20 | 0.76 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.76 |
| ▸ | HTR1A | P08908 | 2/20 | 0.76 |
| ▸ | HRH2 | P25021 | 2/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.76 |
| ▸ | BLM | P54132 | 4/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | CFB | P00751 | 4/20 | 0.55 |
| ▸ | HTR1D | P28221 | 5/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252813 | 0.87 | ADRA2C (0.64) | ADRA2CADRA2AADRA2BADRA1ALMNA | |
| Moxonidine SCHEMBL29363838 | 0.87 | ADRA2C (1.00) | ADRA2CADRA2AADRA2BADRA1ALMNA | |
| Moxonidine SCHEMBL8390103 | 0.87 | ADRA2C (1.00) | ADRA2CADRA2AADRA2BADRA1ALMNA | |
| Moxonidine SCHEMBL49143 | 0.87 | ADRA2C (1.00) | ADRA2CADRA2AADRA2BADRA1ALMNA | |
| SCHEMBL16773670 | 0.85 | ADRA2C (0.66) | ADRA2CADRA2AADRA2BADRA1ALMNA | |
| Moxonidine SCHEMBL1321306 | 0.85 | BLM (1.00) | ADRA2CADRA2AADRA2BADRA1ALMNA | |
| Moxonidine SCHEMBL1230620 | 0.84 | BLM (0.97) | ADRA2CADRA2AADRA2BADRA1ALMNA | |
| Moxonidine SCHEMBL30484346 | 0.84 | BLM (0.97) | ADRA2CADRA2AADRA2BADRA1ALMNA | |
| SCHEMBL11242767 | 0.83 | ADRA2C (0.74) | ADRA2CADRA2AADRA2BADRA1ALMNA | |
| Moxonidine SCHEMBL8007695 | 0.80 | ADRA2C (0.86) | ADRA2CADRA2AADRA2BADRA1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892895-A1 | MOXONIDINE SYNTHESIS WITH THE AID OF ORGANIC BASES | WÖRWAG PHARMA GmbH & Co. KG (DE) | 2015-07-15 | — | — | EP | claimed |
| WO-2014037391-A1 | MOXONIDINE SYNTHESIS WITH THE AID OF ORGANIC BASES | WÖRWAG PHARMA GmbH & Co. KG (DE) | 2014-03-13 | — | — | WO | claimed |
| EP-1894927-B1 | The use of moxonidine salts for purification of moxonidine | CHEMAGIS LTD (IL) | 2010-11-10 | — | — | EP | claimed |
| EP-1894927-A1 | The use of moxonidine salts for purification of moxonidine | CHEMAGIS LTD. (IL) | 2008-03-05 | — | — | EP | claimed |
| EP-2738165-B1 | Method by means of phase transfer catalysis | WÖRWAG PHARMA GMBH & CO KG (DE) | 2016-10-12 | — | — | EP | disclosed |
| EP-2892895-A1 | MOXONIDINE SYNTHESIS WITH THE AID OF ORGANIC BASES | WÖRWAG PHARMA GmbH & Co. KG (DE) | 2015-07-15 | — | — | EP | disclosed |
| EP-2738165-A1 | Method by means of phase transfer catalysis | WÖRWAG PHARMA GmbH & Co. KG (DE) | 2014-06-04 | — | — | EP | disclosed |
| WO-2014037391-A1 | MOXONIDINE SYNTHESIS WITH THE AID OF ORGANIC BASES | WÖRWAG PHARMA GmbH & Co. KG (DE) | 2014-03-13 | — | — | WO | disclosed |
| EP-1982983-B1 | Improved process for producing moxonidine | CHEMAGIS LTD (IL) | 2011-08-17 | — | — | EP | disclosed |
| EP-1982983-B1 | Improved process for producing moxonidine | CHEMAGIS LTD (IL) | 2011-08-17 | — | — | EP | disclosed |
| EP-1894927-B1 | The use of moxonidine salts for purification of moxonidine | CHEMAGIS LTD (IL) | 2010-11-10 | — | — | EP | disclosed |
| EP-1894927-B1 | The use of moxonidine salts for purification of moxonidine | CHEMAGIS LTD (IL) | 2010-11-10 | — | — | EP | disclosed |
| WO-2008073125-A1 | MOXONIDINE ANALOGS, PREPARATION PROCESSES AND USES THEREFOR | CHEMAGIS LTD. (IL) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008073125-A1 | MOXONIDINE ANALOGS, PREPARATION PROCESSES AND USES THEREFOR | CHEMAGIS LTD. (IL) | 2008-06-19 | — | — | WO | disclosed |
| EP-1894927-A1 | The use of moxonidine salts for purification of moxonidine | CHEMAGIS LTD. (IL) | 2008-03-05 | — | — | EP | disclosed |
| EP-1894927-A1 | The use of moxonidine salts for purification of moxonidine | CHEMAGIS LTD. (IL) | 2008-03-05 | — | — | EP | disclosed |
| EP-1873151-A1 | Improved process for producing moxonidine | CHEMAGIS LTD. (IL) | 2008-01-02 | — | — | EP | disclosed |
| EP-1873151-A1 | Improved process for producing moxonidine | CHEMAGIS LTD. (IL) | 2008-01-02 | — | — | EP | disclosed |
| EP-1873152-A1 | Novel purification process of moxonidine | CHEMAGIS LTD. (IL) | 2008-01-02 | — | — | EP | disclosed |
| EP-1873152-A1 | Novel purification process of moxonidine | CHEMAGIS LTD. (IL) | 2008-01-02 | — | — | EP | disclosed |