SCHEMBL2333086

SCHEMBL2333086

O=C(/C=C/c1ccc(O)c(O)c1)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.65
▸ TDP1 Q9NUW8 1/20 0.65
▸ PRKCA P17252 7/20 0.64
▸ HSP90AA1 P07900 1/20 0.59
▸ CYP19A1 P11511 2/20 0.58
▸ ALDH1A1 P00352 1/20 0.57
▸ CYP3A4 P08684 1/20 0.57
▸ ALOX15 P16050 1/20 0.57
▸ MAPK1 P28482 1/20 0.57
▸ HSD17B10 Q99714 1/20 0.57
▸ L3MBTL1 Q9Y468 2/20 0.56
▸ KDM1A O60341 2/20 0.56
▸ BACE1 P56817 1/20 0.56
▸ SNCA P37840 1/20 0.54
▸ AKR1B1 P15121 1/20 0.53
▸ DPP4 P27487 1/20 0.53
▸ CYP46A1 Q9Y6A2 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL546757 1.00 GAA (0.65) GAATDP1PRKCAHSP90AA1CYP19A1
SCHEMBL31487400 1.00 GAA (0.65) GAATDP1PRKCAHSP90AA1CYP19A1
SCHEMBL30669730 1.00 GAA (0.65) GAATDP1PRKCAHSP90AA1CYP19A1
SCHEMBL15711523 1.00 GAA (0.65) GAATDP1PRKCAHSP90AA1CYP19A1
SCHEMBL15147273 1.00 GAA (0.65) GAATDP1PRKCAHSP90AA1CYP19A1
SCHEMBL3986428 1.00 GAA (0.65) GAATDP1PRKCAHSP90AA1CYP19A1
SCHEMBL15144478 1.00 GAA (0.65) GAATDP1PRKCAHSP90AA1CYP19A1
SCHEMBL29531507 1.00 GAA (0.65) GAATDP1PRKCAHSP90AA1CYP19A1
SCHEMBL9234208 0.90 SNCA (0.54) GAATDP1PRKCAHSP90AA1CYP19A1
SCHEMBL9231411 0.90 SNCA (0.54) GAATDP1PRKCAHSP90AA1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118177317-A Functional dry noodle leaf for diabetics and preparation method thereof 河南工业大学 2024-06-14 — — CN claimed
US-9381223-B2 Methods for inhibiting advanced glycation end product production, inhibiting fibroblast apoptosis, and/or promoting human fibroblast-collagen grating formulation using cherry blossom and cherry leaf extract ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2016-07-05 — — US claimed
US-20150174188-A1 METHODS FOR INHIBITING ADVANCED GLYCATION END PRODUCT PRODUCTION, INHIBITING FIBROBLAST APOPTOSIS, AND/OR PROMOTING HUMAN FIBROBLAST-COLLAGEN GRATING FORMULATION USING CHERRY BLOSSOM AND CHERRY LEAF EXTRACT ORYZA OIL & FAT CHEM (JP) 2015-06-25 — — US claimed
US-20130196937-A1 AGE PRODUCTION INHIBITOR ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2013-08-01 — — US claimed
CN-118177317-A Functional dry noodle leaf for diabetics and preparation method thereof 河南工业大学 2024-06-14 — — CN disclosed
CN-116987807-A SNP molecular marker related to polyphenol content of tomato fruits and application thereof 中国农业大学 2023-11-03 — — CN disclosed
CN-106061461-B oral biofilm calcification inhibitor and oral composition 狮王株式会社 2019-02-15 — — CN disclosed
US-9381223-B2 Methods for inhibiting advanced glycation end product production, inhibiting fibroblast apoptosis, and/or promoting human fibroblast-collagen grating formulation using cherry blossom and cherry leaf extract ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2016-07-05 — — US disclosed
US-9381223-B2 Methods for inhibiting advanced glycation end product production, inhibiting fibroblast apoptosis, and/or promoting human fibroblast-collagen grating formulation using cherry blossom and cherry leaf extract ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2016-07-05 — — US disclosed
US-20150174188-A1 METHODS FOR INHIBITING ADVANCED GLYCATION END PRODUCT PRODUCTION, INHIBITING FIBROBLAST APOPTOSIS, AND/OR PROMOTING HUMAN FIBROBLAST-COLLAGEN GRATING FORMULATION USING CHERRY BLOSSOM AND CHERRY LEAF EXTRACT ORYZA OIL & FAT CHEM (JP) 2015-06-25 — — US disclosed
US-20150174188-A1 METHODS FOR INHIBITING ADVANCED GLYCATION END PRODUCT PRODUCTION, INHIBITING FIBROBLAST APOPTOSIS, AND/OR PROMOTING HUMAN FIBROBLAST-COLLAGEN GRATING FORMULATION USING CHERRY BLOSSOM AND CHERRY LEAF EXTRACT ORYZA OIL & FAT CHEM (JP) 2015-06-25 — — US disclosed
CN-102883733-B AGE production inhibitor ORYZA OIL & FAT CHEM 2014-08-13 — — CN disclosed
US-20130196937-A1 AGE PRODUCTION INHIBITOR ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2013-08-01 — — US disclosed
US-20130196937-A1 AGE PRODUCTION INHIBITOR ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2013-08-01 — — US disclosed
CN-102883733-A AGE production inhibitor ORYZA OIL & FAT CHEM 2013-01-16 — — CN disclosed
WO-2011099570-A1 AGE PRODUCTION INHIBITOR オリザ油化株式会社 (JP) 2011-08-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130196937-A1 AGE PRODUCTION INHIBITOR AGER, GLA, GBA3 GAA 5/4885TDP1 2159/4885PRKCA 1873/4885
US-20150174188-A1 METHODS FOR INHIBITING ADVANCED GLYCATION END PRODUCT PRODUCTION, INHIBITING FIBROBLAST APOPTOSIS, AND/OR PROMOTING HUMAN FIBROBLAST-COLLAGEN GRATING FORMULATION USING CHERRY BLOSSOM AND CHERRY LEAF EXTRACT AGER, GLA, COLGALT1 GAA 51/4885TDP1 1748/4885PRKCA 2525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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