⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645224 | 0.65 | GSK3A (0.46) | — | |
| SCHEMBL17546258 | 0.64 | — | — | |
| SCHEMBL12133555 | 0.63 | — | — | |
| SCHEMBL13870106 | 0.62 | — | — | |
| SCHEMBL9921247 | 0.62 | — | — | |
| SCHEMBL2037670 | 0.62 | — | — | |
| SCHEMBL7260943 | 0.62 | — | — | |
| SCHEMBL6179485 | 0.60 | — | — | |
| SCHEMBL19685300 | 0.59 | — | — | |
| SCHEMBL22416283 | 0.59 | BRPF1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087325-A1 | COMPOSITIONS AND METHODS FOR SILENCING DNAJB1-PRKACA FUSION GENE EXPRESSION | ALNYLAM PHARMACEUTICALS, INC. (US) | 2021-05-06 | — | — | WO | disclosed |